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中年阿爾茲海默癥生物標(biāo)志物變化可預(yù)測老年癡呆發(fā)生
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SUZ12抗原;SUZ12重組蛋白多種屬 UZ12是一種多梳組(PcG)蛋白。PcG蛋白通過形成多蛋白復(fù)合物起作用,這是在整個發(fā)育過程中維持同源異型基因轉(zhuǎn)錄抑制狀態(tài)所必需的。PcG蛋白不需要啟動抑制,而是在發(fā)育的后期維持它。它們可能通過組蛋白的甲基化起作用,使染色質(zhì)的表達能力發(fā)生遺傳性變化。SUZ12是PRC2復(fù)合物的一個組分,它甲基化組蛋白H3的Lys-9和Lys-27殘基。
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品牌 | 信裕生物 | CAS | 詳見說明書 |
---|---|---|---|
分子式 | 詳見說明書 | 純度 | > 90% |
分子量 | 26.2kDa | 貨號 | XY94829RPHu |
規(guī)格 | 50µg/100µg | 供貨周期 | 一周 |
主要用途 | SDS-PAGE; WB | 應(yīng)用領(lǐng)域 | 生物產(chǎn)業(yè) |
Recombinant Suppressor Of Zeste 12 Homolog (SUZ12)
Zeste 12同源物1抑制因子2(SUZ12)重組蛋白
[ PROPERTIES ]
Source: Prokaryotic expression
Host: E.coli
Residues: Leu448~Phe639
Tags: N-terminal His Tag
Subcellular Location: Nucleus
Purity: > 90%
Traits: Freeze-dried powder
Buffer formulation: PBS, pH7.4, containing 0.01% SKL, 5% Trehalose.
Original Concentration: 200µg/mL
Applications: Positive Control; Immunogen; SDS-PAGE; WB.
(May be suitable for use in other assays to be determined by the end user.)
Predicted isoelectric point: 6.9
Predicted Molecular Mass: 26.2kDa
Accurate Molecular Mass: 28kDa as determined by SDS-PAGE reducing conditions.
[ USAGE ]
Reconstitute in 10mM PBS (pH7.4) to a concentration of 0.1-1.0 mg/mL. Do not vortex.
[ STORAGE AND STABILITY ]
Storage: Avoid repeated freeze/thaw cycles.
Store at 2-8oC for one month.
Aliquot and store at -80oC for 12 months.
Stability Test: The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37°C for 48h, and no obvious degradation and precipitation were observed. The loss rate is less than 5% within the expiration date under appropriate storage condition.
[SEQUENCE ]
[ IDENTIFICATION ]
[ IMPORTANT NOTE ]
The kit is designed for research use only, we will not be responsible for any issue if the kit was used in clinical diagnostic or any other procedures.
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