含NLR家族Pyrin域蛋白3(NLRP3)重組蛋白

含NLR家族Pyrin域蛋白3(NLRP3)重組蛋白可能作為細(xì)胞凋亡的誘導(dǎo)劑。選擇性地與ASC相互作用，這種復(fù)合物可能作為NF-kappa-B信號(hào)傳導(dǎo)的上游激活劑。抑制TNF-α誘導(dǎo)的RELA/NF-KB p65的活化和核轉(zhuǎn)位。還抑制RELA的轉(zhuǎn)錄活性。激活胱天蛋白酶-1以應(yīng)對(duì)多種觸發(fā)因素，包括細(xì)菌或病毒感染，導(dǎo)致IL1B和IL18的加工和釋放。亞細(xì)胞位置：細(xì)胞質(zhì)。

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更新時(shí)間：2024-12-10
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詳細(xì)介紹

品牌	信裕生物	CAS	詳見(jiàn)說(shuō)明書
分子式	詳見(jiàn)說(shuō)明書	純度	>95%
分子量	33kDa	貨號(hào)	XY93541RPHu01
規(guī)格	50µg/100µg	供貨周期	一周
主要用途	SDS-PAGE; WB	應(yīng)用領(lǐng)域	生物產(chǎn)業(yè)

Recombinant NLR Family, Pyrin Domain Containing Protein 3 (NLRP3)

含NLR家族Pyrin域蛋白3(NLRP3)重組蛋白

[ PROPERTIES ]

Source: Prokaryotic expression

Host: E.coli

Residues: Cys770~Trp1036

Tags: N-terminal His Tag

Subcellular Location: Membrane, Nucleus, Secreted, Cytoplasm, Golgi apparatus,Endoplasmic reticulum lumen

Purity: > 95%

Traits: Freeze-dried powder

Buffer formulation: PBS, pH7.4, containing 0.01% SKL, 5% Trehalose.

Original Concentration: 50µg/mL

Applications: Positive Control; Immunogen; SDS-PAGE; WB.

(May be suitable for use in other assays to be determined by the end user.)

Predicted isoelectric point: 5.7

Predicted Molecular Mass: 33kDa

Accurate Molecular Mass: 33kDa as determined by SDS-PAGE reducing conditions.

[ USAGE ]

Reconstitute in ddH₂O to a concentration less than or equal to 0.1mg/mL. Do not vortex.

[ STORAGE AND STABILITY ]

Storage: Avoid repeated freeze/thaw cycles.

Store at 2-8oC for one month.

Aliquot and store at -80oC for 12 months.

Stability Test: The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37°C for 48h, and no obvious degradation and precipitation were observed. The loss rate is less than 5% within the expiration date under appropriate storage condition.

[SEQUENCE ]

含NLR家族Pyrin域蛋白3(NLRP3)重組蛋白

[ IDENTIFICATION ]

含NLR家族Pyrin域蛋白3(NLRP3)重組蛋白

[ IMPORTANT NOTE ]

The kit is designed for research use only, we will not be responsible for any issue if the kit was used in clinical diagnostic or any other procedures.

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