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TERF1相互作用核因子2(TINF2)重組蛋白 shelterin復(fù)合體(端粒體)的一種成分,參與端粒長(zhǎng)度的調(diào)節(jié)和保護(hù)。Shelterin與端粒酶添加的雙鏈TTAGGG重復(fù)序列結(jié)合,保護(hù)染色體末端;如果沒(méi)有它的保護(hù)活性,端粒就不再隱藏在DNA損傷監(jiān)測(cè)之外,染色體末端也被DNA修復(fù)途徑不當(dāng)處理。在復(fù)雜的裝配中起著重要作用。異構(gòu)體1可能在將端粒連接到核基質(zhì)中發(fā)揮額外作用。
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品牌 | 信裕生物 | CAS | 詳見(jiàn)說(shuō)明書(shū) |
---|---|---|---|
分子式 | 詳見(jiàn)說(shuō)明書(shū) | 純度 | >95% |
分子量 | 53.6kDa | 貨號(hào) | XY94924RPHu |
規(guī)格 | 50µg/100µg | 供貨周期 | 一周 |
主要用途 | SDS-PAGE; WB | 應(yīng)用領(lǐng)域 | 生物產(chǎn)業(yè) |
Recombinant TERF1 Interacting Nuclear Factor 2 (TINF2)
TERF1相互作用核因子2(TINF2)重組蛋白
[ PROPERTIES ]
Source: Prokaryotic expression
Host: E.coli
Residues: Ala2~Leu451
Tags: N-terminal His Tag
Subcellular Location: Nucleus, Chromosome
Purity: > 95%
Traits: Freeze-dried powder
Buffer formulation: PBS, pH7.4, containing 0.01% SKL, 5% Trehalose.
Original Concentration: 200µg/mL
Applications: Positive Control; Immunogen; SDS-PAGE; WB.
(May be suitable for use in other assays to be determined by the end user.)
Predicted isoelectric point: 8.0
Predicted Molecular Mass: 53.6kDa
Accurate Molecular Mass: 54kDa as determined by SDS-PAGE reducing conditions.
[ USAGE ]
Reconstitute in 20mM Tris, 150mM NaCl (pH8.0) to a concentration of 0.1-1.0 mg/mL. Do not vortex.
[ STORAGE AND STABILITY ]
Storage: Avoid repeated freeze/thaw cycles.
Store at 2-8oC for one month.
Aliquot and store at -80oC for 12 months.
Stability Test: The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37°C for 48h, and no obvious degradation and precipitation were observed. The loss rate is less than 5% within the expiration date under appropriate storage condition.
[SEQUENCE ]
[ IDENTIFICATION ]
[ IMPORTANT NOTE ]
The kit is designed for research use only, we will not be responsible for any issue if the kit was used in clinical diagnostic or any other procedures.
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