60kDa多聚U結(jié)合剪接因子(PUF60)重組蛋白

PUF60抗原；60kDa多聚U結(jié)合剪接因子(PUF60)重組蛋白多種屬該基因編碼一種核酸結(jié)合蛋白，在多種核過(guò)程中發(fā)揮作用，包括前mRNA剪接和轉(zhuǎn)錄調(diào)控。編碼的蛋白質(zhì)與骨髓細(xì)胞瘤癌基因（MYC）啟動(dòng)子處的遠(yuǎn)上游DNA元件（FUSE）和FUSE結(jié)合蛋白形成復(fù)合物。該復(fù)合物通過(guò)核心TFIIH基礎(chǔ)轉(zhuǎn)錄因子抑制MYC轉(zhuǎn)錄。或者，已經(jīng)觀察到該基因編碼多種異構(gòu)體的剪接轉(zhuǎn)錄變體?！居蒖efSeq提供，2012

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廠商性質(zhì)：生產(chǎn)廠家
更新時(shí)間：2025-02-19
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詳細(xì)介紹

品牌	信裕生物	CAS	詳見(jiàn)說(shuō)明書(shū)
分子式	詳見(jiàn)說(shuō)明書(shū)	純度	> 90%
分子量	64.6kDa	貨號(hào)	XY93948RPHu
規(guī)格	50µg/100µg	供貨周期	一周
主要用途	SDS-PAGE; WB	應(yīng)用領(lǐng)域	生物產(chǎn)業(yè)

Recombinant Poly U Binding Splicing Factor 60kDa (PUF60)

60kDa多聚U結(jié)合剪接因子(PUF60)重組蛋白

[ PROPERTIES ]

Source: Prokaryotic expression

Host: E.coli

Residues: Asn226~Gln549

Tags: N-terminal His and GST Tag

Subcellular Location: Nucleus

Purity: > 90%

Traits: Freeze-dried powder

Buffer formulation: 20mM Tris, 150mM NaCl, pH8.0, containing 0.01% SKL, 5% Trehalose.

Original Concentration: 200µg/mL

Applications: Positive Control; Immunogen; SDS-PAGE; WB.

(May be suitable for use in other assays to be determined by the end user.)

Predicted isoelectric point: 5.0

Predicted Molecular Mass: 64.6kDa

Accurate Molecular Mass: 65kDa as determined by SDS-PAGE reducing conditions.

[ USAGE ]

Reconstitute in 20mM Tris, 150mM NaCl (pH8.0) to a concentration of 0.1-1.0 mg/mL. Do notvortex.

[ STORAGE AND STABILITY ]

Storage: Avoid repeated freeze/thaw cycles.

Store at 2-8oC for one month.

Aliquot and store at -80oC for 12 months.

Stability Test: The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37°C for 48h, and no obvious degradation and precipitation were observed. The loss rate is less than 5% within the expiration date under appropriate storage condition.

[SEQUENCE ]

60kDa多聚U結(jié)合剪接因子(PUF60)重組蛋白

[ IDENTIFICATION ]

60kDa多聚U結(jié)合剪接因子(PUF60)重組蛋白

[ IMPORTANT NOTE ]

The kit is designed for research use only, we will not be responsible for any issue if the kit was used in clinical diagnostic or any other procedures.

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