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線粒體蛋白酪氨酸磷酸酶1(PTPMT1)重組蛋白

線粒體蛋白酪氨酸磷酸酶1(PTPMT1)重組蛋白 是硫嘌呤類藥物(如硫唑嘌呤、巰嘌呤和硫鳥嘌呤)的代謝中最主要的酶之一,起到的作用是在這類化合物的硫原子上增加一個甲基;這個過程中提供甲基的是S-腺苷甲硫氨酸,后者同時被轉(zhuǎn)化成S-腺苷-L-高半胱氨酸。 TPMT基因的缺陷會讓人體無法將這類藥物滅活,未代謝的藥物因此在體內(nèi)大量累積,從而引起嚴(yán)重甚至致命的骨髓抑制,表現(xiàn)為貧血、血小板減少癥(導(dǎo)致

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  • 廠商性質(zhì):生產(chǎn)廠家
  • 更新時間:2025-03-31
  • 訪  問  量:158
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詳細(xì)介紹
品牌信裕生物CAS詳見說明書
分子式詳見說明書純度> 95%
分子量26.9kDa貨號XY94203RPHu
規(guī)格50µg/100µg供貨周期一周
主要用途SDS-PAGE; WB應(yīng)用領(lǐng)域生物產(chǎn)業(yè)

Recombinant Protein Tyrosine Phosphatase, Mitochondrial 1 (PTPMT1) 

線粒體蛋白酪氨酸磷酸酶1(PTPMT1)重組蛋白

[ PROPERTIES ]

Source:Prokaryotic expression

Host: E.coli

Residues: Leu26~His227

Tags:N-terminal His Tag

Tissue Specificity: Kidney, Bone marrow, Cervix carcinoma, Liver.

Subcellular Location: Cytoplasm

Purity: > 95%

Traits:Freeze-dried powder

Buffer formulation: 100mM NaHCO3, 500mM NaCl, pH8.3, containing1mMEDTA, 1mM DTT, 0.01% sarcosyl, 5%Trehalose and Proclin300.

Original Concentration:200µg/mL

Applications:Positive Control; Immunogen; SDS-PAGE; WB.

(May be suitable for use in other assays to be determined by the end user.)

Predicted isoelectric point:6.7

Predicted Molecular Mass: 26.9kDa

Accurate Molecular Mass: 27kDa as determined by SDS-PAGE reducingconditions

[ USAGE ]

Reconstitute in 100mM NaHCO3, 500mM NaCl (pH8.3) to a concentrationof0.1-1.0 mg/mL. Do not vortex.

[ STORAGE AND STABILITY ]

Storage: Avoid repeated freeze/thaw cycles.

           Store at 2-8oC for one month.

           Aliquot and store at -80oC for 12 months.

Stability Test: The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37°C for 48h, and no obvious degradation and precipitation were observed. The loss rate is less than 5% within the expiration date under appropriate storage condition.

[SEQUENCE ]

線粒體蛋白酪氨酸磷酸酶1(PTPMT1)重組蛋白

[  IDENTIFICATION  ]

線粒體蛋白酪氨酸磷酸酶1(PTPMT1)重組蛋白

[ IMPORTANT NOTE ]

The kit is designed for research use only, we will not be responsible for any issue if the kit was used in clinical diagnostic or any other procedures.

特別提示:本公司的所有產(chǎn)品僅可用于科研實驗,嚴(yán)禁用于臨床醫(yī)療及其他非科研用途!以實際收貨產(chǎn)品說明書為準(zhǔn),網(wǎng)站說明書僅供參考!


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